[2] Colo Colo 3-0 Santiago Wanderers [17] 2021-11-06 21:00
Stadium: Monumental David Arellano Round: 31
Referee: Felipe Gonzalez Home Manager: Gustavo Quinteros Away Manager: Emiliano Astorga
Head to Head
| Chile - Primera Division | 2021/07/29 19:00 | Santiago Wanderers v Colo Colo | W | 0-4 |
| Chile - Primera Division | 2021/01/06 13:30 | Santiago Wanderers v Colo Colo | L | 3-0 |
| Chile - Primera Division | 2020/08/29 17:30 | Colo Colo v Santiago Wanderers | L | 2-3 |
| Chile - Superpohár | 2018/01/26 22:00 | Colo Colo v Santiago Wanderers | W | 3-0 |
| Chile Apertura | 2017/10/15 18:30 | Colo Colo v Santiago Wanderers | W | 2-0 |
| Chile Clausura | 2017/03/11 15:00 | Santiago Wanderers v Colo Colo | W | 0-2 |
| Chile Apertura | 2016/09/24 15:00 | Colo Colo v Santiago Wanderers | D | 1-1 |
| Chile Clausura | 2016/04/30 19:00 | Colo Colo v Santiago Wanderers | W | 2-1 |
| Chile Apertura | 2016/01/11 21:00 | Santiago Wanderers v Colo Colo | L | 2-1 |
| Chile Clausura | 2015/05/02 18:30 | Colo Colo v Santiago Wanderers | W | 3-1 |
| Chile Apertura | 2014/12/06 20:00 | Santiago Wanderers v Colo Colo | L | 2-0 |