[2] Colo Colo 3-0 Santiago Wanderers [17] 2021-11-06 21:00
Stadium: Monumental David Arellano Round: 31
Referee: Felipe Gonzalez Home Manager: Gustavo Quinteros Away Manager: Emiliano Astorga
Head to Head
| Chile - Primera Division | 2021/07/29 19:00 | Santiago Wanderers v Colo Colo | W | 0-4 |
| Chile - Primera Division | 2021/01/06 13:30 | Santiago Wanderers v Colo Colo | L | 3-0 |
| Chile - Primera Division | 2020/08/29 17:30 | Colo Colo v Santiago Wanderers | L | 2-3 |
| Chile - Superpohár | 2018/01/26 22:00 | Colo Colo v Santiago Wanderers | W | 3-0 |
| Chile Apertura | 2017/10/15 18:30 | Colo Colo v Santiago Wanderers | W | 2-0 |
| Chile Clausura | 2017/03/11 15:00 | Santiago Wanderers v Colo Colo | W | 0-2 |
| Chile Apertura | 2016/09/24 15:00 | Colo Colo v Santiago Wanderers | D | 1-1 |
| Chile Clausura | 2016/04/30 19:00 | Colo Colo v Santiago Wanderers | W | 2-1 |
Home History
| Chile - Primera Division | 2021/10/28 21:00 | Audax Italiano v Colo Colo | L | 2-0 |
| Chile - Primera Division | 2021/10/24 19:30 | Colo Colo v Universidad Catolica | W | 2-1 |
| Chile - Primera Division | 2021/10/20 17:00 | La Serena v Colo Colo | W | 1-4 |
| Chile - Primera Division | 2021/10/09 23:30 | Colo Colo v Huachipato | W | 2-0 |
| Chile - Primera Division | 2021/10/03 18:30 | Palestino v Colo Colo | W | 1-2 |
| Chile - Primera Division | 2021/09/30 21:30 | Colo Colo v Nublense | L | 0-1 |
| Chile - Primera Division | 2021/09/26 19:30 | Universidad de Chile v Colo Colo | W | 1-3 |
| Chile - Primera Division | 2021/09/14 22:00 | Colo Colo v Everton de Vina | W | 2-0 |
Away History
| Chile - Primera Division | 2021/10/29 18:30 | Santiago Wanderers v Palestino | D | 1-1 |
| Chile - Primera Division | 2021/10/25 15:30 | Santiago Wanderers v CD Antofagasta | L | 0-1 |
| Chile - Primera Division | 2021/10/20 21:30 | Universidad Catolica v Santiago Wanderers | L | 3-2 |
| Chile - Primera Division | 2021/10/16 18:00 | Santiago Wanderers v Everton de Vina | W | 2-1 |
| Chile - Primera Division | 2021/10/11 19:00 | O'Higgins v Santiago Wanderers | L | 1-0 |
| Chile - Primera Division | 2021/10/04 21:30 | Melipilla v Santiago Wanderers | D | 1-1 |
| Chile - Primera Division | 2021/09/29 19:00 | Santiago Wanderers v Universidad de Chile | W | 2-1 |
| Chile - Primera Division | 2021/09/26 15:00 | Nublense v Santiago Wanderers | W | 1-2 |