| NCAAF | 09/11 17:00 | 1 | [118] Eastern Illinois v Dayton [48] | L | 10-17 | |
| NCAAF | 09/04 23:00 | 1 |
Eastern Illinois
v
South Carolina
|
L | 0-46 | |
| NCAAF | 08/28 22:00 | 1 | Eastern Illinois v Indiana State | L | 21-26 | |
| NCAAF | 04/11 18:00 | 1 |
Austin Peay
v
Eastern Illinois
|
- | Postponed | |
| NCAAF | 04/03 18:00 | 1 | Jacksonville State v Eastern Illinois | L | 44-23 | |
| NCAAF | 03/28 19:00 | 1 | Eastern Illinois v Murray State | L | 27-41 | |
| NCAAF | 03/21 18:00 | 1 | Tennessee Tech University v Eastern Illinois | W | 20-28 | |
| NCAAF | 03/14 18:00 | 1 | Eastern Illinois v Tennessee State | L | 20-21 | |
| NCAAF | 03/07 19:00 | 1 | Eastern Illinois v Tennessee Martin | L | 15-28 | |
| NCAAF | 02/28 20:00 | 1 | Eastern Illinois v SE Missouri St | L | 7-47 | |
| NCAAF | 11/23 20:00 | 1 |
Eastern Illinois
v
Austin Peay
|
L | 7-35 | |
| NCAAF | 11/16 18:00 | 1 | SE Missouri St v Eastern Illinois | L | 26-12 | |
| NCAAF | 11/09 20:00 | 1 | Eastern Illinois v Tennessee State | W | 49-38 | |
| NCAAF | 10/26 19:00 | 1 | Eastern Kentucky v Eastern Illinois | L | 33-6 | |
| NCAAF | 10/19 19:00 | 1 | Eastern Illinois v Tennessee Martin | L | 18-27 | |
| NCAAF | 10/12 17:00 | 1 | Jacksonville State v Eastern Illinois | L | 28-20 | |
| NCAAF | 10/05 18:00 | 1 | Eastern Illinois v Murray St | L | 17-24 | |
| NCAAF | 09/28 21:00 | 1 | Tennessee Tech University v Eastern Illinois | L | 40-29 | |
| NCAAF | 09/21 17:00 | 1 | Eastern Illinois v Indiana St | L | 6-16 | |
| NCAAF | 09/14 19:00 | 1 | Illinois St v Eastern Illinois | L | 21-3 | |
| NCAAF | 09/07 19:30 | 1 |
Eastern Illinois
v
Indiana
|
L | 0-52 | |
| NCAAF | 08/29 23:00 | 1 | Eastern Illinois v Chattanooga | L | 10-24 | |
| NCAAF FCS | 11/17 19:00 | 1 | Eastern Illinois v SE Missouri St | L | 32-38 | |
| NCAAF FCS | 11/10 19:00 | 1 |
Austin Peay
v
Eastern Illinois
|
W | 21-52 | |
| NCAAF | 10/27 17:00 | 1 | Eastern Kentucky v Eastern Illinois | L | 31-23 | |
| NCAAF | 10/20 19:00 | 1 | Eastern Illinois v Tennessee Martin | W | 24-21 | |
| NCAAF | 10/13 20:00 | 1 | Eastern Illinois v Jacksonville State | L | 22-49 | |
| NCAAF | 10/06 23:00 | 1 | Murray St v Eastern Illinois | L | 48-41 | |
| NCAAF | 09/29 23:00 | 1 | Eastern Illinois v Tennessee Tech University | W | 52-38 | |
| NCAAF | 09/22 19:00 | 1 | Tennessee State v Eastern Illinois | L | 41-40 |