[10] La Serena 0-0 Santiago Wanderers [17] 2021-12-04 21:00
Stadium: La Portada Round: 34
Referee: Maria Carvajal Home Manager: Ivo Basay Away Manager: Jorge Luis Omar Garces Rojas
Head to Head
| Chile - Primera Division | 2021/08/21 15:30 | Santiago Wanderers v La Serena | D | 2-2 |
| Chile - Primera Division | 2021/01/18 20:00 | Santiago Wanderers v La Serena | D | 0-0 |
| Chile - Primera Division | 2020/02/23 15:00 | La Serena v Santiago Wanderers | W | 3-0 |
| Chile - Primera B | 2019/09/14 23:00 | Santiago Wanderers v La Serena | L | 4-1 |
| Chile - Primera B | 2019/05/11 19:30 | La Serena v Santiago Wanderers | D | 0-0 |
| Chile - Primera B | 2018/09/24 21:00 | La Serena v Santiago Wanderers | D | 1-1 |
| Chile - Primera B | 2018/04/21 18:00 | Santiago Wanderers v La Serena | D | 1-1 |
| Chile - Pohár | 2016/07/17 19:00 | Santiago Wanderers v La Serena | L | 2-1 |
| Chile - Pohár | 2016/07/09 00:00 | La Serena v Santiago Wanderers | W | 3-1 |