Stadium: Alumni Stadium Round: 1
| NCAAF | 2021/10/09 18:00 | Rose Hulman Engineers v Hanover Panthers | L | 31-21 |
| NCAAF | 2019/11/09 19:00 | Rose Hulman Engineers v Hanover Panthers | W | 13-42 |
| NCAAF | 2018/11/03 18:00 | Hanover Panthers v Rose Hulman Engineers | W | 29-14 |
| NCAAF | 2022/10/29 17:30 | Anderson Ravens v Hanover Panthers | W | 3-62 |
| NCAAF | 2022/10/22 17:30 | Hanover Panthers v Mount St. Joseph Lions | L | 29-44 |
| NCAAF | 2022/10/15 17:30 | Manchester Spartans v Hanover Panthers | W | 20-51 |
| NCAAF | 2022/10/08 17:30 | Hanover Panthers v Bluffton Beavers | W | 63-21 |
| NCAAF | 2022/10/01 17:30 | Defiance Yellow Jackets v Hanover Panthers | W | 20-37 |
| NCAAF | 2022/09/17 17:00 | Hanover Panthers v Olivet Comets | L | 28-31 |
| NCAAF | 2022/09/10 17:00 | Adrian Bulldogs v Hanover Panthers | L | 33-0 |
| NCAAF | 2022/09/03 17:00 | Hanover Panthers v Centre Colonels | L | 29-31 |
| NCAAF | 2022/10/29 17:30 | Rose Hulman Engineers v Defiance Yellow Jackets | W | 76-35 |
| NCAAF | 2022/10/22 17:30 | Rose Hulman Engineers v Franklin College Grizzlies | W | 49-0 |
| NCAAF | 2022/10/15 17:30 | Bluffton Beavers v Rose Hulman Engineers | W | 20-48 |
| NCAAF | 2022/10/08 18:00 | Rose Hulman Engineers v Manchester Spartans | W | 48-14 |
| NCAAF | 2022/10/01 17:30 | Anderson Ravens v Rose Hulman Engineers | W | 7-45 |
| NCAAF | 2022/09/17 16:00 | Rose Hulman Engineers v Albion Britons | L | 17-49 |
| NCAAF | 2022/09/10 23:00 | Rose Hulman Engineers v Trine Thunder | L | 23-24 |
| NCAAF | 2022/09/03 17:00 | Depauw Tigers v Rose Hulman Engineers | L | 17-14 |