[14] Union Santa Fe 1-5 River Plate [26] 2022-06-19 21:00
Stadium: Estadio 15 de Abril Round: 4
Referee: Pablo Echavarria Home Manager: Gustavo Munua Away Manager: Marcelo Gallardo
Head to Head
| Argentina - Liga Profesional | 2022/02/12 22:15 | Union Santa Fe v River Plate | W | 1-0 |
| Argentina - Liga Profesional | 2021/07/25 21:00 | River Plate v Union Santa Fe | L | 4-0 |
| Argentina - Superliga | 2020/02/10 00:45 | Union Santa Fe v River Plate | L | 1-2 |
| Argentina - Superliga | 2019/01/24 00:00 | River Plate v Union Santa Fe | W | 1-2 |
| Argentina - Superliga | 2017/11/22 22:15 | River Plate v Union Santa Fe | L | 2-0 |
| Argentina - Superliga | 2017/03/12 22:10 | River Plate v Union Santa Fe | D | 0-0 |
| Argentina - Pohár | 2016/10/28 00:10 | River Plate v Union Santa Fe | L | 3-0 |
| Argentina - Liga Profesional | 2015/03/08 21:15 | River Plate v Union Santa Fe | D | 2-2 |
Home History
| Argentina - Liga Profesional | 2022/06/15 17:00 | Barracas Central v Union Santa Fe | W | 1-2 |
| Argentina - Liga Profesional | 2022/06/12 16:00 | Colon v Union Santa Fe | D | 2-2 |
| Argentina - Liga Profesional | 2022/06/05 16:00 | Union Santa Fe v CA Tigre | L | 1-2 |
| Copa Sudamericana | 2022/05/27 00:30 | Junior v Union Santa Fe | W | 0-4 |
| Copa Sudamericana | 2022/05/19 22:15 | Union Santa Fe v Fluminense | D | 0-0 |
| Argentina - Liga Profesional | 2022/05/08 19:00 | Argentinos Jrs v Union Santa Fe | L | 2-1 |
| Copa Sudamericana | 2022/05/05 22:15 | Union Santa Fe v Oriente Petrolero | W | 2-0 |
| Argentina - Liga Profesional | 2022/05/02 22:00 | Union Santa Fe v Defensa y Justicia | L | 1-2 |
Away History
| Argentina - Liga Profesional | 2022/06/15 22:00 | Colon v River Plate | L | 1-0 |
| Argentina - Liga Profesional | 2022/06/11 23:30 | River Plate v Atlético Tucumán | D | 0-0 |
| Argentina - Liga Profesional | 2022/06/06 00:30 | Defensa y Justicia v River Plate | D | 0-0 |
| Copa Libertadores | 2022/05/25 22:00 | River Plate v Alianza Lima | W | 8-1 |
| Copa Libertadores | 2022/05/20 00:00 | River Plate v Colo Colo | W | 4-0 |
| Argentina - Liga Profesional | 2022/05/12 00:30 | River Plate v CA Tigre | L | 1-2 |
| Argentina - Liga Profesional | 2022/05/09 00:00 | River Plate v Platense | W | 2-1 |
| Copa Libertadores | 2022/05/05 22:00 | Fortaleza EC v River Plate | D | 1-1 |