[14] Club América 2-3 Atletico San Luis [18] 2022-02-06 01:00
Stadium: Estadio Azteca Round: 4
Referee: Adonai Escobedo Gonzalez Home Manager: Santiago Hernan Solari Poggio Away Manager: Marcelo Mendez
Head to Head
| Mexiko - Liga MX | 2021/10/17 00:00 | Atletico San Luis v Club América | W | 0-1 |
| Mexiko - Liga MX | 2021/01/10 03:00 | Club América v Atletico San Luis | W | 2-1 |
| Mexiko - Liga MX | 2020/08/30 00:00 | Atletico San Luis v Club América | W | 1-2 |
| Mexiko - Liga MX | 2019/10/30 01:00 | Atletico San Luis v Club América | W | 0-1 |
| Mexiko - Pohár | 2019/01/31 03:00 | Atletico San Luis v Club América | L | 2-0 |
| Mexiko - Pohár | 2019/01/24 03:00 | Club América v Atletico San Luis | W | 1-0 |
Home History
| Mexiko - Liga MX | 2022/01/23 03:00 | Club América v Atlas | L | 0-2 |
| Mexiko - Liga MX | 2022/01/08 03:00 | Puebla v Club América | D | 1-1 |
| Mexiko - Liga MX | 2021/11/28 01:00 | Club América v Unam Pumas | L | 1-3 |
| Mexiko - Liga MX | 2021/11/25 01:00 | Unam Pumas v Club América | D | 0-0 |
| Mexiko - Liga MX | 2021/11/07 01:00 | Club América v Monterrey | D | 0-0 |
| Mexiko - Liga MX | 2021/10/31 23:05 | Cruz Azul v Club América | L | 2-1 |
| CONCACAF Champions Cup | 2021/10/29 02:00 | Monterrey v Club América | L | 1-0 |
| Mexiko - Liga MX | 2021/10/24 00:00 | Club América v Tigres UANL | W | 1-0 |
Away History
| Mexiko - Liga MX | 2022/01/21 03:00 | Atletico San Luis v Juarez FC | L | 0-1 |
| Mexiko - Liga MX | 2022/01/15 23:00 | Atlas v Atletico San Luis | L | 1-0 |
| Mexiko - Liga MX | 2022/01/07 03:00 | Atletico San Luis v Pachuca | L | 0-2 |
| Svět - Přátelská utkání klubů | 2021/12/23 23:00 | Atletico San Luis v Necaxa | W | 3-1 |
| Mexiko - Liga MX | 2021/11/21 01:00 | Santos Laguna v Atletico San Luis | L | 2-0 |
| Mexiko - Liga MX | 2021/11/08 01:06 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Mexiko - Liga MX | 2021/11/04 01:00 | Pachuca v Atletico San Luis | D | 0-0 |
| Mexiko - Liga MX | 2021/11/01 01:05 | Atletico San Luis v Monterrey | D | 1-1 |