Stadium: Convocation Center Ohio
Home Manager: Jeff Boals Away Manager: Dave Dickerson
| NCAAB | 2021/12/18 21:00 | USC Upstate v Converse Valkyries | W | 78-38 |
| NCAAB | 2021/12/15 00:00 | USC Upstate v Tennessee | L | 52-96 |
| NCAAB | 2021/12/12 00:00 | USC Upstate v Wake Forest | L | 53-79 |
| NCAAB | 2021/12/04 23:00 | Western Carolina v USC Upstate | L | 78-73 |
| NCAAB | 2021/12/01 21:00 | North Carolina Central v USC Upstate | L | 67-65 |
| NCAAB | 2021/11/27 21:00 | Furman v USC Upstate | L | 87-77 |
| NCAAB | 2021/11/24 00:00 | USC Upstate v South Carolina State | W | 82-78 |
| NCAAB | 2021/11/19 00:00 | USC Upstate v East Tenn St | L | 43-56 |
| NCAAB | 2021/12/16 00:00 | Marshall v Ohio | W | 65-75 |
| NCAAB | 2021/12/11 20:00 | Ohio v Stetson | W | 55-45 |
| NCAAB | 2021/12/04 20:30 | St Francis PA v Ohio | W | 75-78 |
| NCAAB | 2021/12/02 01:00 | Ohio v LSU | L | 51-66 |
| NCAAB | 2021/11/26 21:00 | Ohio v Concordia (Mi) Cardinals | W | 88-68 |
| NCAAB | 2021/11/23 00:00 | Mount St Marys v Ohio | W | 59-73 |
| NCAAB | 2021/11/20 00:00 | Ohio v Kentucky | L | 59-77 |
| NCAAB | 2021/11/16 00:00 | Robert Morris v Ohio | W | 71-85 |