Stadium: Campo Directv Round: 26 Ground: Clay
| Challenger Bogota | 2021/10/19 15:00 | Alexis Gautier v Matheus P De Almeida | 2-6,1-6 |
| Challenger Santiago | 2021/10/16 17:00 | Felipe Meligeni Rodrigues Alves v Matheus P De Almeida | 6-2,6-4 |
| Challenger Santiago | 2021/10/15 19:40 | Matheus P De Almeida v Francisco Cerundolo | 7-6,2-6,6-4 |
| Challenger Santiago | 2021/10/13 16:35 | Matheus P De Almeida v Nicolas Kicker | 3-6,6-2,6-4 |
| Challenger Santiago | 2021/10/12 18:40 | Enzo Couacaud v Matheus P De Almeida | 1-6,1-6 |
| Challenger Santiago | 2021/10/05 14:00 | Matheus P De Almeida v Alexis Gautier | 6-4,1-6,3-6 |
| Challenger Lima | 2021/09/29 17:05 | Matheus P De Almeida v Johan Nikles | 6-7,4-6 |
| Challenger Lima | 2021/09/27 20:15 | Francisco Cerundolo v Matheus P De Almeida | 2-6,4-6 |
| Challenger Bogota | 2021/10/18 19:10 | Alejandro Gonzalez v Vít Kopřiva | 6-2,7-6 |
| Challenger Lima | 2021/09/27 15:00 | Jorge Panta v Alejandro Gonzalez | 7-5,7-5 |
| Challenger Lima | 2021/09/26 16:00 | Arklon H D Pino v Alejandro Gonzalez | 4-6,7-6,6-7 |
| Challenger Ambato | 2021/09/21 15:00 | Alejandro Gonzalez v Pedro Sakamoto | 3-6,4-6 |
| Challenger Ambato | 2021/09/20 15:00 | Alejandro Gonzalez v Pol Martin Tiffon | 3-6,4-6 |
| Challenger Ambato | 2021/09/19 17:10 | Alejandro Gonzalez v Alejandro Mendoza | 6-2,6-2 |
| Challenger Quito | 2021/09/16 15:00 | Pol Martin Tiffon v Alejandro Gonzalez | 4-6,7-6,6-3 |
| Challenger Quito | 2021/09/14 19:35 | Alejandro Gonzalez v Luca Castelnuovo | 6-2,7-6 |