Stadium: Spec Martin Stadium Round: 1
Home Manager: Brian Young Away Manager: Glenn Caruso
| NCAAF | 2021/10/09 18:00 | Valparaiso v St.Thomas MIN | W | 13-20 |
| NCAAF | 2021/10/02 20:00 | St.Thomas MIN v San Diego | L | 24-27 |
| NCAAF | 2021/09/25 17:00 | Butler v St.Thomas MIN | W | 0-36 |
| NCAAF | 2021/09/11 17:10 | Michigan Technological University Huskies v St.Thomas MIN | W | 9-12 |
| NCAAF | 2019/11/16 19:00 | St.Thomas MIN v Bethel Royals | W | 17-7 |
| NCAAF | 2019/11/09 19:00 | St.Thomas MIN v Gustavus Adolphus Gusties | W | 57-36 |
| NCAAF | 2019/11/02 18:00 | St Olaf Oles v St.Thomas MIN | W | 7-56 |
| NCAAF | 2019/10/26 18:00 | Carleton Knights v St.Thomas MIN | W | 15-63 |
| NCAAF | 2021/10/09 16:00 | Stetson Hatters v Marist | L | 3-34 |
| NCAAF | 2021/10/02 17:00 | Davidson Wildcats v Stetson Hatters | L | 35-28 |
| NCAAF | 2021/09/25 17:00 | Stetson Hatters v Princeton | L | 0-63 |
| NCAAF | 2021/09/11 22:00 | Stetson Hatters v Ave Maria Gyrenes | W | 49-16 |
| NCAAF | 2021/09/04 22:00 | Stetson Hatters v Warner Royals | W | 54-14 |
| NCAAF | 2021/04/10 20:00 | Stetson Hatters v San Diego | L | 10-34 |
| NCAAF | 2021/04/03 17:00 | Presbyterian v Stetson Hatters | L | 26-3 |
| NCAAF | 2021/03/20 16:00 | Stetson Hatters v Morehead State | L | 14-31 |