SE Missouri State 30-14 Austin Peay 2021-10-09 20:00
Stadium: Fortera Stadium Round: 1
Home Manager: Marquase Lovings Away Manager: Tom Matukewicz
Head to Head
| NCAAF | 2021/03/14 19:00 | Austin Peay v SE Missouri St | L | 49-42 |
| NCAAF | 2019/10/12 19:00 | SE Missouri St v Austin Peay | L | 24-28 |
| NCAAF | 2018/10/13 18:00 | Austin Peay v SE Missouri St | W | 27-31 |
| NCAAF | 2017/10/21 21:00 | Austin Peay v SE Missouri St | L | 38-31 |
Home History
| NCAAF | 2021/10/02 18:30 | SE Missouri St v Tennessee Tech University | L | 17-28 |
| NCAAF | 2021/09/25 19:00 | Tennessee State v SE Missouri St | W | 14-47 |
| NCAAF | 2021/09/18 16:00 | SE Missouri St v Missouri | L | 28-59 |
| NCAAF | 2021/09/11 23:00 | SE Missouri St v Sam Houston State | L | 14-52 |
| NCAAF | 2021/09/02 23:30 | SO Illinois v SE Missouri St | L | 47-21 |
| NCAAF | 2021/04/11 19:30 | SE Missouri St v Tennessee State | W | 46-23 |
| NCAAF | 2021/04/03 18:00 | SE Missouri St v Tennessee Martin | W | 21-16 |
| NCAAF | 2021/03/28 19:00 | Tennessee Tech University v SE Missouri St | W | 21-24 |
Away History
| NCAAF | 2021/10/03 00:00 | Tennessee State v Austin Peay | L | 24-22 |
| NCAAF | 2021/09/25 19:00 | Austin Peay v Eastern Kentucky | L | 27-35 |
| NCAAF | 2021/09/18 19:00 | Morehead State v Austin Peay | W | 35-59 |
| NCAAF | 2021/09/11 23:30 | Austin Peay v Mississippi | L | 17-54 |
| NCAAF | 2021/09/02 23:30 | Austin Peay v Tennessee Chattanooga | W | 30-20 |
| NCAAF | 2021/04/03 19:00 | Murray State v Austin Peay | W | 31-34 |
| NCAAF | 2021/03/28 19:00 | Austin Peay v Jacksonville State | W | 13-10 |
| NCAAF | 2021/03/21 19:00 | Tennessee Martin v Austin Peay | L | 37-34 |