[17] Unam Pumas 1-0 Santos Laguna [6] 2021-03-05 03:00
Stadium: Estadio Olimpico Universitario Round: 9
Referee: Jorge Isaac Rojas Castillo Home Manager: Andres Lillini Away Manager: Guillermo Almada
Head to Head
| Mexiko - Liga MX | 2020/09/10 02:06 | Santos Laguna v Unam Pumas | W | 1-2 |
| Mexiko - Liga MX | 2020/02/02 03:00 | Santos Laguna v Unam Pumas | D | 1-1 |
| Mexiko - Pohár | 2020/01/30 01:00 | Unam Pumas v Santos Laguna | W | 2-1 |
| Mexiko - Pohár | 2020/01/23 03:00 | Santos Laguna v Unam Pumas | L | 4-2 |
| Mexiko - Liga MX | 2019/09/29 17:00 | Unam Pumas v Santos Laguna | W | 2-0 |
| Mexiko - Liga MX | 2019/05/05 23:06 | Santos Laguna v Unam Pumas | L | 5-2 |
| Mexiko - Liga MX | 2018/11/25 18:00 | Unam Pumas v Santos Laguna | D | 1-1 |
| Mexiko - Liga MX | 2018/04/22 23:00 | Santos Laguna v Unam Pumas | W | 1-2 |
Home History
| Mexiko - Liga MX | 2021/03/01 03:00 | Chivas Guadalajara v Unam Pumas | L | 2-1 |
| Mexiko - Liga MX | 2021/02/21 18:00 | Unam Pumas v Leon | L | 0-1 |
| Mexiko - Liga MX | 2021/02/14 18:00 | Toluca v Unam Pumas | L | 1-0 |
| Mexiko - Liga MX | 2021/02/07 03:00 | Monterrey v Unam Pumas | L | 1-0 |
| Mexiko - Liga MX | 2021/01/31 18:00 | Unam Pumas v Atlas | D | 0-0 |
| Mexiko - Liga MX | 2021/01/25 01:00 | Queretaro v Unam Pumas | L | 2-0 |
| Mexiko - Liga MX | 2021/01/17 18:00 | Unam Pumas v Mazatlán FC | W | 3-0 |
| Mexiko - Liga MX | 2021/01/09 03:06 | Tijuana v Unam Pumas | D | 0-0 |
Away History
| Mexiko - Liga MX | 2021/03/01 01:06 | Santos Laguna v Juarez FC | W | 3-2 |
| Mexiko - Liga MX | 2021/02/19 03:00 | Atletico San Luis v Santos Laguna | L | 1-0 |
| Mexiko - Liga MX | 2021/02/15 01:06 | Santos Laguna v Monterrey | W | 1-0 |
| Mexiko - Liga MX | 2021/02/06 23:00 | Atlas v Santos Laguna | D | 1-1 |
| Mexiko - Liga MX | 2021/02/01 01:06 | Santos Laguna v Club América | D | 1-1 |
| Mexiko - Liga MX | 2021/01/23 03:30 | Mazatlán FC v Santos Laguna | D | 0-0 |
| Mexiko - Liga MX | 2021/01/18 01:06 | Santos Laguna v Tigres UANL | W | 2-0 |
| Mexiko - Liga MX | 2021/01/11 01:06 | Santos Laguna v Cruz Azul | W | 1-0 |