Head to Head
| NCAAF | 2009/10/17 12:00 | Michigan State v Northwestern | L | 24-14 |
| NCAAF | 2008/10/11 12:00 | Northwestern v Michigan State | L | 20-37 |
| NCAAF | 2007/10/06 12:00 | Michigan State v Northwestern | W | 41-48 |
| NCAAF | 2006/10/21 12:00 | Northwestern v Michigan State | L | 38-41 |
| NCAAF | 2005/10/22 12:00 | Michigan State v Northwestern | W | 14-49 |
| NCAAF | 2002/09/28 12:00 | Michigan State v Northwestern | L | 39-24 |
| NCAAF | 2001/09/29 12:00 | Northwestern v Michigan State | W | 27-26 |
| NCAAF | 2000/09/30 12:00 | Michigan State v Northwestern | W | 17-37 |
Home History
| NCAAF | 2010/10/09 12:00 | Northwestern v Purdue | L | 17-20 |
| NCAAF | 2010/10/02 12:00 | Minnesota v Northwestern | W | 28-29 |
| NCAAF | 2010/09/25 12:00 | Northwestern v Central Michigan | W | 30-25 |
| NCAAF | 2010/09/18 12:00 | Rice v Northwestern | W | 13-30 |
| NCAAF | 2010/09/11 12:00 | Northwestern v Illinois State | W | 37-3 |
| NCAAF | 2010/09/04 12:00 | Vanderbilt v Northwestern | W | 21-23 |
| NCAA Bowl Games | 2010/01/01 12:00 | Auburn v Northwestern | L | 38-35 |
| NCAAF | 2009/11/21 12:00 | Northwestern v Wisconsin | W | 33-31 |
Away History
| NCAAF | 2010/10/16 12:00 | Michigan State v Illinois | W | 26-6 |
| NCAAF | 2010/10/09 12:00 | Michigan v Michigan State | W | 17-34 |
| NCAAF | 2010/10/02 12:00 | Michigan State v Wisconsin | W | 34-24 |
| NCAAF | 2010/09/25 12:00 | Michigan State v Northern Colorado | W | 45-7 |
| NCAAF | 2010/09/18 12:00 | Michigan State v Notre Dame | W | 34-31 |
| NCAAF | 2010/09/11 12:00 | Michigan State v Florida Atlantic | W | 30-17 |
| NCAAF | 2010/09/04 12:00 | Michigan State v Western Michigan | W | 38-14 |
| NCAA Bowl Games | 2010/01/02 12:00 | Michigan State v Texas Tech | L | 31-41 |